RT Journal Article SR Electronic T1 The Impact of Diabetes on the CNS JF Diabetes JO Diabetes FD American Diabetes Association SP 557 OP 570 DO 10.2337/diab.41.5.557 VO 41 IS 5 A1 McCall, Anthony L YR 1992 UL http://diabetes.diabetesjournals.org/content/41/5/557.abstract AB The brain is not usually thought to be a target of chronic diabetes complications. Nonetheless, substantial evidence, summarized herein, suggests that diabetes causes brain damage. Clinical syndromes of diabetes-related brain abnormalities are discussed along with possible causes. Various physiological effects of diabetes are reviewed, and questions are raised about gaps in our knowledge. Appropriate directions for future research are suggested.