Table 1

Subject characteristics

ABCA1Low HDL-C
HomozygousHeterozygousControl subjectsCase subjectsControl subjects
Sex (n)
 Male25577
 Female13322
Race (n)
 Caucasian37777
 African American01122
Age (years)25 ± 1128 ± 728 ± 626 ± 626 ± 4
BMI (kg/m2)25 ± 425 ± 425 ± 325 ± 225 ± 2
Glucose (mg/dL)95 ± 986 ± 1089 ± 989 ± 488 ± 7
Insulin (µU/mL)13.8 ± 1.2*10.3 ± 4.78.4 ± 3.59.1 ± 6.77.1 ± 2.2
Total cholesterol (mg/dL)74 ± 21157 ± 24181 ± 27158 ± 36175 ± 27
Triglyceride (mg/dL)127 ± 59115 ± 5975 ± 32134 ± 44*84 ± 45
HDL-C (mg/dL)2 ± 027 ± 765 ± 1730 ± 465 ± 10
LDL-C (mg/dL)57 ± 26*105 ± 2297 ± 2097 ± 2494 ± 21
VLDL-C (mg/dL)16 ± 624 ± 2219 ± 830 ± 1717 ± 10
ApoA-I (mg/dL)8 ± 383 ± 12159 ± 38100 ± 13155 ± 20
ApoB (mg/dL)76 ± 1486 ± 1668 ± 1583 ± 2066 ± 19
  • Data are means ± SD.

  • ApoA-I, apoprotein A-I; ApoB, apoprotein B.

  • *P < 0.05 case vs. control subjects.

  • P < 0.001 case vs. control subjects.

  • P < 0.0001 case vs. control subjects.