Table 1

Blood glucose, body weight, and kidney weight of STZ-induced and leptin receptor–deficient (db/db) diabetic mice

Blood glucose (mg/dL)Glycoalbumin (%)Body weight (g)Kidney weight (g)
2 weeks after STZ12 weeks after STZ12 weeks after STZRightLeft
STZ-induced mice
 Vehicle358.7 ± 24.3567.0 ± 9.933.6 ± 1.524.7 ± 0.80.31 ± 0.020.31 ± 0.02
 RAGE vaccine369.6 ± 21.6538.7 ± 10.833.4 ± 2.123.6 ± 0.80.28 ± 0.010.28 ± 0.01
db/db mice
 Vehicle383.2 ± 10.050.3 ± 1.80.30 ± 0.010.30 ± 0.01
 RAGE vaccine376.2 ± 10.052.7 ± 2.30.27 ± 0.020.24 ± 0.02*
  • Data are expressed as means ± SEM; differences between mean values of treatment groups were evaluated for significance using the Student t test.

  • * P < 0.05.