Table 2

Circulating blood levels in sham-operated and UniNx mice

Sham-operatedUniNx
ChowHFDChowHFD
Glucose (mmol/L)7.8 ± 0.711.7 ± 0.8##8.8 ± 0.411.9 ± 0.8##
 N710810
Insulin (ng/mL)1.6 ± 0.27.0 ± 0.6###0.9 ± 0.1**5.9 ± 0.8###
 N710810
FFA (mmol/L)ND0.72 ± 0.9ND0.79 ± 0.9
 N55
Creatinine (mg/dL)ND0.59 ± 0.03ND0.72 ± 0.03*
 N79
Uric acid (mg/dL)ND4.4 ± 0.4ND5.4 ± 0.8
 N89
Angiotensin I (ng/mL)20.9 ± 2.020.6 ± 1.529.4 ± 1.8**26.5 ± 1.5*
 N6869
Bile acids (µmol/L)8.4 ± 3.19.4 ± 1.38.2 ± 2.314.0 ± 4.0
 N710810
  • ND, not determined.

  • ##P < 0.01 compared with chow-fed mice.

  • ###P < 0.001 compared with chow-fed mice.

  • **P < 0.01 compared with sham-operated mice.

  • *P < 0.05 compared with sham-operated mice.