Table 3

AROC (95% CI) and the false-positive detection rates for the combined data

OR (95% CI)
top vs. bottom quintileAROC for combined studies
(95% CI)Detection rate for 5% false positive
(95% CI)Detection rate for 10% false positive
(95% CI)
Externally weighted gene score2.70 (2.12–3.43)0.60 (0.58–0.62)11.75% (9.54–13.95)19.89% (17.14–22.63)
FORS21.07 (14.86–29.88)0.75 (0.73–0.77)18.56% (15.9–21.22)30.67% (27.51–33.82)
FORS + externally weighted gene score22.59 (15.75–32.41)0.76 (0.75–0.78)*23.14% (20.23–26.05)37.28% (33.95–40.61)
  • *P = 0.003. P value derived from the comparison with FORS alone.