Table 1

Physiological and biochemical parameters

ParametersGroups
BAMBI+/+ citrate 
(n = 6)BAMBI−/− citrate 
(n = 5)BAMBI+/+ STZ 
(n = 7)BAMBI−/− STZ 
(n = 8)
Body weight before injection (g)23.57 ± 1.719.6 ± 0.624.1 ± 1.821.80 ± 1.4
Kidney–to–body weight ratio (mg/g)7.2 ± 0.46.7 ± 0.49.9 ± 0.6*Δξ9.6 ± 0.5*Δ
Blood pressure (mmHg)
 Systolic98 ± 5105 ± 3110 ± 6100 ± 8
 Diastolic77 ± 679 ± 380 ± 670 ± 7
Serum creatinine (mg/dL)0.16 ± 0.020.16 ± 0.010.17 ± 0.010.14 ± 0.004
Urinary albumin excretion (μg/24 hours)21.9 ± 3.931.5 ± 8.7103.8 ± 11 *Δ207.0 ± 32 *Δξ
  • *P < 0.05 vs. BAMBI+/+ citrate.

  • ΔP < 0.05 vs. BAMBI−/− citrate.

  • ξP < 0.05 vs. BAMBI+/+ STZ.