Table 1

Maternal type 2 diabetes induces NTD formation

GroupFasting glucose (mmol/L)Random glucose (mmol/L)Number of embryosResorption rate (%)NTD rate (%)
Ctrl 1 (n = 15)5.08 ± 0.547.06 ± 0.351193 (2.5)0 (0.0)
DM (n = 16)7.92 ± 0.51*9.56 ± 0.23*10626 (19.7)*12 (11.3)*
Ctrl 2 (n = 15)5.76 ± 0.547.38 ± 0.261074 (3.6)0 (0.0)
  • Data are mean ± SD unless otherwise indicated. Ctrl 1 group fed normal diet, DM group fed HFD, and Ctrl 2 group fed 60% HFD during pregnancy.

  • *Significant differences compared with the other two groups as analyzed by the Tukey or χ2 test.