Table 3

Cardiovascular responses during hyperinsulinemic-euglycemic and hyperinsulinemic-hypoglycemic clamps

BasalFinal
Systolic blood pressure (mmHg)
 Day 1 eugly110 ± 3110 ± 3
 Day 2 hypo after day 1 eugly109 ± 3116 ± 4
 Day 1 hypo112 ± 4121 ± 7
 Day 2 hypo after day 1 hypo113 ± 4123 ± 5
Diastolic blood pressure (mmHg)
 Day 1 eugly63 ± 262 ± 2
 Day 2 hypo after day 1 eugly65 ± 160 ± 2
 Day 1 hypo65 ± 262 ± 3
 Day 2 hypo after day 1 hypo66 ± 162 ± 2
Mean arterial pressure (mmHg)
 Day 1 eugly79 ± 276 ± 3
 Day 2 hypo after day 1 eugly80 ± 280 ± 2
 Day 1 hypo81 ± 382 ± 4
 Day 2 hypo after day 1 hypo81 ± 283 ± 3
Heart rate (bpm)
 Day 1 eugly64 ± 367 ± 2
 Day 2 hypo after day 1 eugly65 ± 374 ± 2
 Day 1 hypo66 ± 370 ± 3
 Day 2 hypo after day 1 hypo68 ± 375 ± 2
  • Data are means ± SE. eugly, euglycemia; hypo, hypoglycemia.

  • P < 0.05 compared with baseline.

  • P < 0.05 compared with final euglycemia.