Table 1

Body length and weight of adipose tissue depots and liver in Stk25 KO mice and WT littermates

ParameterWT CDKO CDWT HFDKO HFD
Body length (cm)8.98 ± 0.109.00 ± 0.119.53 ± 0.16††9.50 ± 0.08##
eWAT (g)1.57 ± 0.161.17 ± 0.131.84 ± 0.202.10 ± 0.24##
eWAT (% body weight)4.31 ± 0.363.30 ± 0.40*4.43 ± 0.355.18 ± 0.32
Liver (g)1.38 ± 0.091.34 ± 0.071.77 ± 0.201.57 ± 0.14
Liver (% body weight)3.80 ± 0.233.78 ± 0.194.26 ± 0.353.87 ± 0.25
  • Data are mean ± SEM from 10–12 mice per genotype and diet group. The body length and adipose tissue depot and liver weights were estimated in mice fed an HFD for 20 weeks compared with age-matched CD groups. CD, chow diet; HFD, high-fat diet; KO, knockout; WT, wild type.

  • *P < 0.05 for Stk25−/− mice vs. corresponding WT littermates;

  • ††P < 0.01 for WT mice fed HFD vs. CD;

  • ##P < 0.01 for Stk25−/− mice fed HFD vs. CD.