Table 1

Thirty-three miRNAs differentially expressed in CVB5-infected human islets compared with uninfected control

miRNADysregulation*Fold-changedpiRank of abundance in β-cells (x/518)§
625-5pDown14.354
365b-3pDown9.244, 7353
34a-5pUp8.224115
149-5pDown7.714334
99b-3pDown7.694247
182-5pDown7.31716
21-3pUp7.167191
93-3pDown5.934419
216b-5pDown5.074
376c-3pDown4.914, 7
193b-3pDown4.854423
432-5pDown4.54762
339-3pDown4.534204
181a-2-3pDown4.417330
425-3pDown4.304174
183-3pDown4.174, 7321
155-5pUp4.071385
1290Up4.017
493-3pDown3.887273
217Down3.837167
30a-3pDown3.824164
30e-3pDown3.484, 7108
345-5pDown3.447209
720Down3.394335
885-5pDown3.387440
29a-3pDown3.35457
191-5pDown3.2849
663bUp3.277
186-5pDown3.22440
10b-3pUp3.217
411-5pDown3.194, 743
181a-3pDown3.151
629-3pDown3.034
  • miRNAs are listed in the order of highest to lowest fold change.

  • *Direction of dysregulation.

  • †Fold difference in miRNA levels between CVB5-infected and uninfected human islets.

  • ‡The dpi at which they were dysregulated.

  • §Rank (x/518) of abundance (number of reads/total number of reads) among 518 total miRNAs detected by Hi-Seq in healthy human pancreatic β-cells (7).