TABLE 4

Sensitivity and specificity of combined assays

nSensitivityComposite 95% CISpecificityComposite 95% CI
Both cellular assays520.530.29–0.760.940.86–1.0
Either cellular assays470.950.85–1.00.780.63–0.93
Both cellular assays and either autoantibody570.350.12–0.591.00.92–1.0
Either cellular assay and either autoantibody580.750.55–0.901.00.92–1.0
Either autoantibody620.780.61–0.960.850.72–0.95
Both autoantibodies620.480.26–0.700.970.92–1.0