TABLE 2

Association of TCF7L2 rs12255372 (T/G) genotypes with covariates among diabetes-free control subjects in U.S. Caucasian women and men

CovariateWomenMen
GGGTTTP*GGGTTTP*
n5644097847136362
Age (years)56.5 ± 6.956.2 ± 6.757.4 ± 7.40.3756.9 ± 8.656.5 ± 8.555.1 ± 7.00.26
BMI (kg/m2)27.3 ± 6.027.4 ± 5.827.1 ± 5.80.9025.2 ± 2.924.9 ± 2.724.7 ± 2.80.32
Physical activity (MET hours/week)16.0 ± 19.514.3 ± 16.413.2 ± 15.00.2424.1 ± 32.420.8 ± 25.018.9 ± 19.40.16
Family history of diabetes in first-degree relatives22.823.020.50.8911.914.316.10.46
Never smokers47.148.050.00.3846.547.946.80.79
Postmenopausal status79.379.982.00.61
History of hypertension31.632.420.50.1118.115.424.20.21
History of high cholesterol38.336.342.30.5612.39.99.70.51
  • Data are means ± SD or percent.

  • * ANOVA was used to compare geometric mean levels of continuous characteristics across genotypes.