TABLE 2

Histochemical analysis of the islet infiltration by immune cells in immunocompromised and immunocompetent models

Days after treatment
123456 / 710 / 1114 / 15
CD4+
    Balb/c−/+++++++++++++++++
    Scid
CD8+
    Balb/c++++++++++++++++
    Scid−/+
CD19+
    Balb/c++++++++++
    Scid−/+−/+
CD68+
    Balb/c++++++++++++++++++++++++++
    Scid+++++++++++++
Neutrophils
    Balb/c+++++++++++++++++++++
    Scid−/+−/++−/+−/+−/+
  • Scoring: −/+, at least one cell in the islet was positive; + to +++++, increasing degree of infiltration.