TABLE 1

Characteristics of the subjects studied

Case samplesControl samples
W2SPW2CW2TP*58BCHRC+
n5721,5863882,024550
Male (%)54.461.859.450.150.3
Age at examination (years)64.1 ± 8.160.2 ± 8.246.3 ± 7.1Not availableNot known
Age at diagnosis (years)55.3 ± 8.451.4 ± 7.540.3 ± 7.7Not applicableNot applicable
BMI (kg/m2)28.4 (24.0–33.7)31.5 (25.9–38.2)32.3 (26.2–39.8)Not availableNot known
Waist-to-hip ratio
    Men0.95 (0.89–1.03)0.98 (0.92–1.05)0.98 (0.91–1.05)Not availableNot known
    Women0.87 (0.80–0.93)0.91 (0.84–0.99)0.89 (0.81–0.98)Not availableNot known
Treatment (ins/OHA/diet) (%)16/69/158/62/3118/63/19Not applicableNot applicable
  • Data are means ± SD or geometric means (SD range).

  • * Results given for all trio probands (n = 388). Of these, 350 were of British/Irish origin (60% male; age at diagnosis 40.3 ± 7.4 years; BMI 32.3 kg/m2 [26.3–39.6]).

  • Treatment at the time of ascertainment. ins, insulin; OHA, oral hypoglycemic agent.