TABLE 1

Summary of SNPs typed in Caucasian individual samples for DUSP12 region

Location	Name	Alleles	Case frequency	Control frequency	P allelic	P additive	P recessive	P dominant
−34702	rs905595	G/C	0.255	0.250	0.704	0.900	0.830	1.00
−32767	rs2050887	A/G	0.042	0.034	0.356	0.700	1.00	0.700
−27665	rs905591	C/G	0.121	0.139	0.526	0.690	0.450	0.630
−23504	rs1417582	G/A	0.288	0.312	0.431	0.092	0.37	0.121
−22594	rs1875763	C/G	0.516	0.481	0.269	0.500	0.290	0.730
−16394	rs905589	C/T	0.356	0.389	0.301	0.640	0.460	0.460
−16193	rs905590	T/C	0.042	0.064	0.155	0.340	0.500	0.240
−10473	rs1503814	A/G	0.234	0.314	0.015	0.039	0.180	0.022
−10381	rs12021510	T/C	0.053	0.070	0.365	0.664	1.00	0.430
−10275	rs17415059	G/A	0.379	0.414	0.333	0.398	1.00	0.460
−10082	Novel	1 bp Del/Ins	0.166	0.219	0.067	0.154	0.33	0.085
−8798	rs6657266	G/A	0.052	0.057	0.978	ND	ND	0.870
−8797	rs17415066	C/T	0.073	0.067	0.790	ND	0.24	0.550
−8379	rs6143445	STR (x/194)	0.297	0.196	0.0008	0.0003	1.00	0.00011
−8340	rs1340981	T/C	0.437	0.356	0.0134	0.056	0.041	0.106
−6735	rs1027702	C/T	0.428	0.351	0.0172	0.092	0.14	0.052
−6229	rs10917821	C/G	0.377	0.306	0.0143	0.092	0.119	0.077
−5606	rs4657096	G/A	0.446	0.356	0.0072	0.036	0.036	0.052
−4559	rs2174208	C/T	0.429	0.358	0.0293	0.078	0.038	0.196
−3795	rs6687091	C/T	0.388	0.413	0.490	0.681	0.440	1.00
−2299	rs10917835	T/A	0.053	0.054	0.844	ND	ND	1.00
−1726	Novel	CT Ins/Del	0.407	0.337	0.027	0.037	0.743	0.013
−852	rs6427625	C/G	0.432	0.36	0.016	0.113	0.140	0.083
−643	rs6427626	G/T	0.479	0.415	0.052	0.213	0.248	0.147
−377	rs12121310	A/C	0.379	0.308	0.026	0.096	0.166	0.06
−213	rs953301	G/A	0.044	0.048	0.795	ND	ND	0.715
838	Novel	C/G	0.291	0.321	0.377	0.427	1.00	0.25
1759	rs7540096	A/G	0.495	0.418	0.035	0.105	0.159	0.068
2115	rs1063178	G/A	0.382	0.291	0.008	0.023	0.123	0.012
2612	rs1063179	G/A	0.051	0.059	0.788	ND	ND	0.623
2680	rs10917852	G/T	0.377	0.411	0.344	0.445	1.00	0.278
4935	rs12564653	T/C	0.484	0.410	0.042	0.118	0.194	0.071
6140	rs12026369	C/G	0.032	0.060	0.062	ND	ND	0.071
6180	rs4656332	G/A	0.43	0.359	0.048	0.133	0.192	0.084
6705	rs10527814	STR (x/194)	0.326	0.218	0.001	0.0002	0.00007	0.85
7359	rs16863049	C/G	0.045	0.044	0.946	0.595	ND	1.00
7580	rs3820449	C/T	0.294	0.194	0.0015	0.00018	1.00	0.0001
10157	rs1417580	G/T	0.482	0.407	0.043	0.102	0.192	0.056
10309	rs1417581	G/C	0.476	0.413	0.082	0.175	0.299	0.094
16444	rs2298019	G/A	0.130	0.148	0.4794	0.769	0.682	0.558

SNPs that were in complete linkage disequilibrium (r² = 1) were typed only in 48 control samples and are not included. Likewise, SNPs with low minor allele frequencies (<5%) were generally not tested. Raw counts are available in supplemental Table 2, which is detailed in the online appendix. P values are shown for allelic tests, additive genotypic model (P additive), rare allele recessive model (P recessive), and rare allele dominant model (P dominant). ND, not determined where rare allele was uncommon and hence homozygotes were not observed.