TABLE 1

Summary of SNPs typed in Caucasian individual samples for DUSP12 region

LocationNameAllelesCase frequencyControl frequencyP allelicP additiveP recessiveP dominant
−34702rs905595G/C0.2550.2500.7040.9000.8301.00
−32767rs2050887A/G0.0420.0340.3560.7001.000.700
−27665rs905591C/G0.1210.1390.5260.6900.4500.630
−23504rs1417582G/A0.2880.3120.4310.0920.370.121
−22594rs1875763C/G0.5160.4810.2690.5000.2900.730
−16394rs905589C/T0.3560.3890.3010.6400.4600.460
−16193rs905590T/C0.0420.0640.1550.3400.5000.240
−10473rs1503814A/G0.2340.3140.0150.0390.1800.022
−10381rs12021510T/C0.0530.0700.3650.6641.000.430
−10275rs17415059G/A0.3790.4140.3330.3981.000.460
−10082Novel1 bp Del/Ins0.1660.2190.0670.1540.330.085
−8798rs6657266G/A0.0520.0570.978NDND0.870
−8797rs17415066C/T0.0730.0670.790ND0.240.550
−8379rs6143445STR (x/194)0.2970.1960.00080.00031.000.00011
−8340rs1340981T/C0.4370.3560.01340.0560.0410.106
−6735rs1027702C/T0.4280.3510.01720.0920.140.052
−6229rs10917821C/G0.3770.3060.01430.0920.1190.077
−5606rs4657096G/A0.4460.3560.00720.0360.0360.052
−4559rs2174208C/T0.4290.3580.02930.0780.0380.196
−3795rs6687091C/T0.3880.4130.4900.6810.4401.00
−2299rs10917835T/A0.0530.0540.844NDND1.00
−1726NovelCT Ins/Del0.4070.3370.0270.0370.7430.013
−852rs6427625C/G0.4320.360.0160.1130.1400.083
−643rs6427626G/T0.4790.4150.0520.2130.2480.147
−377rs12121310A/C0.3790.3080.0260.0960.1660.06
−213rs953301G/A0.0440.0480.795NDND0.715
838NovelC/G0.2910.3210.3770.4271.000.25
1759rs7540096A/G0.4950.4180.0350.1050.1590.068
2115rs1063178G/A0.3820.2910.0080.0230.1230.012
2612rs1063179G/A0.0510.0590.788NDND0.623
2680rs10917852G/T0.3770.4110.3440.4451.000.278
4935rs12564653T/C0.4840.4100.0420.1180.1940.071
6140rs12026369C/G0.0320.0600.062NDND0.071
6180rs4656332G/A0.430.3590.0480.1330.1920.084
6705rs10527814STR (x/194)0.3260.2180.0010.00020.000070.85
7359rs16863049C/G0.0450.0440.9460.595ND1.00
7580rs3820449C/T0.2940.1940.00150.000181.000.0001
10157rs1417580G/T0.4820.4070.0430.1020.1920.056
10309rs1417581G/C0.4760.4130.0820.1750.2990.094
16444rs2298019G/A0.1300.1480.47940.7690.6820.558
  • SNPs that were in complete linkage disequilibrium (r2 = 1) were typed only in 48 control samples and are not included. Likewise, SNPs with low minor allele frequencies (<5%) were generally not tested. Raw counts are available in supplemental Table 2, which is detailed in the online appendix. P values are shown for allelic tests, additive genotypic model (P additive), rare allele recessive model (P recessive), and rare allele dominant model (P dominant). ND, not determined where rare allele was uncommon and hence homozygotes were not observed.