TABLE 1

Body mass, fat mass, and oxygen consumption in standard diet–and fat-fed mice

5 weeks20 weeks
Standard dietFatStandard dietFat
Body mass (g)28.7 ± 0.528.8 ± 0.531.7 ± 0.735.9 ± 0.8*
Fat mass (%)14.5 ± 1.324.8 ± 1.9*13.9 ± 0.627.8 ± 2.9*
Epididymal fat mass (g)0.28 ± 0.020.63 ± 0.05*0.46 ± 0.091.71 ± 0.21*
Brown fat mass (mg)68 ± 376 ± 479 ± 8130 ± 2*
Vo2 (ml/g/h)3.57 ± 0.053.72 ± 0.063.42 ± 0.033.43 ± 0.10
RER (Vco2/Vo2)0.96 ± 0.010.86 ± 0.01*0.95 ± 0.010.81 ± 0.01*
  • Data are means ± SE of 6–11 animals per group. Fat mass (%) was determined by dual-energy X-ray absorptiometry scanning. Vo2 and RER (respiratory exchange ratio) represents the average values recorded over a 24-h period.

  • * P < 0.01 vs. standard diet–fed mice.