TABLE 1

Body mass, fat mass, and oxygen consumption in standard diet–and fat-fed mice

	5 weeks		20 weeks
	Standard diet	Fat	Standard diet	Fat
Body mass (g)	28.7 ± 0.5	28.8 ± 0.5	31.7 ± 0.7	35.9 ± 0.8*
Fat mass (%)	14.5 ± 1.3	24.8 ± 1.9*	13.9 ± 0.6	27.8 ± 2.9*
Epididymal fat mass (g)	0.28 ± 0.02	0.63 ± 0.05*	0.46 ± 0.09	1.71 ± 0.21*
Brown fat mass (mg)	68 ± 3	76 ± 4	79 ± 8	130 ± 2*
Vo₂ (ml/g/h)	3.57 ± 0.05	3.72 ± 0.06	3.42 ± 0.03	3.43 ± 0.10
RER (Vco₂/Vo₂)	0.96 ± 0.01	0.86 ± 0.01*	0.95 ± 0.01	0.81 ± 0.01*

Data are means ± SE of 6–11 animals per group. Fat mass (%) was determined by dual-energy X-ray absorptiometry scanning. Vo₂ and RER (respiratory exchange ratio) represents the average values recorded over a 24-h period.
* P < 0.01 vs. standard diet–fed mice.