TABLE 2

Plasma cytokine levels

Cytokines (pg/ml)Wild typeNormo-glycemic L1Diabetic L1
IL-1β37.6 ± 4.446.9 ± 9.746.2 ± 5.2
IL-233.6 ± 1.434.0 ± 1.5ND
IL-624.5 ± 2.128.3 ± 4.727.8 ± 2.2
IL-12119.9 ± 27.4121.4 ± 13.6ND
GM-CSF24.4 ± 3.831.7 ± 7.131.2 ± 4.2
TNFα36.4 ± 0.937.7 ± 2.238.6 ± 1.6
  • Data are means ± SE. Measurements were made in 3-month-old male mice under fed conditions. GM-CSF, granulocyte-macrophage colony-stimulating factor; ND, not determined; TNF, tumor necrosis factor.