TABLE 2

IA-2 sequence variations in IA-2 autoantibody–positive patients

Patient no.ExonsType of mutationNucleotide changeAmino acid change
13SilentC298→TNone
7MissenseA1137→GE137→G
213SilentG1921→ANone
35MissenseC579→TA169→V
46MissenseT909→AL279→H
18SilentT2557→CNone
54MissenseC441→AP123→L
5MissenseC528→TA152→V
65SilentT475→CNone