TABLE 1

Diabetic mice injected with 2 × 109 pfu of null adenovirus or SREBP-1c adenovirus and studied 18 h later

Enzyme activitySTZ + adenovirus nullSTZ + adenovirus SREBP-1c
n89
Glucokinase20.6 ± 0.736.2 ± 1.0*
FAS7.9 ± 0.716.9 ± 1.0*
PEPCK12.6 ± 1.53.4 ± 0.2*
  • Data are means ± SD (in milliunits per milligrams protein). Liver was quickly removed and frozen at −80°C for subsequent enzyme activity determination.

  • *

    * Difference statistically significant for P < 0.001.