TABLE 3

Values of inflammation markers stratified by tertiles of BMI and FG status at follow-up

No change in statusNormal → IFGNormal → diabetes
BMI < 24.4
n1,1683511
 CRP (mg/l)1.2 (1.7)1.4 (2.5)*3.3 (10.4)*
 Fibrinogen (g/l)3.1 (0.6)3.2 (0.7)3.0 (0.8)
 Albumin (g/l)40.0 (3.0)40.0 (3.0)40.0 (3.0)
 WBC count (103/mm3)6.0 (2.0)6.6 (1.4)6.5 (1.2)
 Factor VIIIc (g/l)1.2 (0.3)1.3 (0.4)1.3 (0.4)
 Platelet count (103/mm3)244 (73)265 (74)273 (73)
24.4 < BMI < 27.9
n1,0765413
 CRP (mg/l)1.6 (1.9)1.7 (2.5)1.6 (1.5)
 Fibrinogen (g/l)3.2 (0.6)3.2 (0.7)3.1 (0.4)
 Albumin (g/l)40.0 (3.0)41.0 (3.0)41.0 (3.0)
 WBC count (103/mm3)6.1 (1.8)6.2 (1.5)5.5 (1.9)
 Factor VIIIc (g/l)1.2 (0.4)1.1 (0.3)1.2 (0.4)
 Platelet count (103/mm3)242 (66)235 (56)220 (57)
BMI > 27.9
n7607521
 CRP (mg/l)2.2 (2.3)2.3 (2.3)3.1 (4.7)
 Fibrinogen (g/l)3.3 (0.6)3.0 (0.6)*3.5 (0.8)+
 Albumin (g/l)40.0 (3.0)40.0 (3.0)40.0 (3.0)
 WBC count (103/mm3)6.1 (1.6)6.3 (1.4)6.7 (1.8)
 Factor VIIIc (g/l)1.2 (0.3)1.2 (0.3)1.2 (0.3)
 Platelet count (103/mm3)248 (66)240 (60)249 (88)
  • Values are means (SD) except for CRP, which is presented as median with interquartile ranges.

  • *

    * Significantly different (P < 0.05) than the group without change in glycemic status;

  • significantly different from the Normal → IFG group. For participants with no diabetes at baseline, data were missing for the following: CRP, 16 (0.5%); fibrinogen, 20 (0.6%); WBC count, 11 (0.3%); factor VIII, 314 (9.7%); platelet count, 24 (0.7%). Ten participants were missing BMI values and are not included in this analysis. WBC, white blood cell.