TABLE 1

Metabolic parameters in mice with or without APOC1 overexpression

GenotypeBody weight (g)Nasal-anal length (cm)Food intake (g/day)Lipid absorption (% of dietary intake)Body temperature (°C)
Wild-type background
 Wild-type23.7 ± 0.99.2 ± 0.44.5 ± 0.592.9 ± 0.837.6 ± 0.4
 APOC119.6 ± 0.98.7 ± 0.3*5.6 ± 1.291.3 ± 0.637.1 ± 0.3*
ob/ob background
ob/ob43.8 ± 7.19.3 ± 0.56.0 ± 1.892.0 ± 0.736.2 ± 0.4
ob/ob APOC121.1 ± 4.17.8 ± 0.54.8 ± 1.691.2 ± 1.136.4 ± 0.7
  • Data are the means ± SD of seven mice per group. Male mice of the respective genotypes were compared at the age of 3 months. Food intake, lipid absorption, and body temperature were measured as described in research design and methods.

  • *

    * P < 0.05 versus wild-type mice;

  • P < 0.05 versus ob/ob mice.