TABLE 2

Clinical characteristics of the two groups of patients with uremia and type 1 diabetes undergoing KA or KP transplantation at the moment of the study

ParametersKP (n = 60)KA (n = 30)P value
Age (years)42.5 ± 1.045.3 ± 1.4NS
Duration of treatment (years [range])3.5 ± 0.3 (1.3–6.0)3.7 ± 0.2 (1.5–6.1)NS
Smoking habit (n)21/6012/30NS
Hypertension (n)38/6020/30NS
Systolic blood pressure (mmHg)135.3 ± 4.5138.2 ± 3.6NS
Diastolic blood pressure (mmHg)81.1 ± 2.085.2 ± 3.1NS
Antihypertensive drugs assumed (n)0.9 ± 0.11.3 ± 0.2NS
Creatinine (mg/dl)1.10 ± 0.041.2 ± 0.07NS
Cyclosporine (ng/ml)190.2 ± 7.8187.2 ± 6.9NS
Blood glucose (mg/dl)90.2 ± 2.7193.8 ± 14.2<0.01
GHb (%)6.2 ± 0.18.4 ± 0.5<0.01
Serum C-peptide (ng/ml)1.43 ± 0.080.02 ± 0.01<0.01
Serum free insulin (μU/ml)16.9 ± 2.226.0 ± 3.5<0.01
Cholesterol (mg/dl)214.0 ± 8.23231.0 ± 11.7NS
Triglycerides (mg/dl)122.7 ± 8.6187.0 ± 30.10.01
Folate (ng/dl)6.8 ± 0.55.4 ± 0.5NS
Vitamin B12 (pg/ml)525.2 ± 41.3626.4 ± 107.2NS
Urinary albumin excretion rate (mg/24 h)13.5 ± 1.957.3 ± 26.3<0.01
Fasting tHcy (μmol/l)14.0 ± 0.719.0 ± 2.00.02
Postload tHcy (μmol/l)33.5 ± 2.633.8 ± 2.7NS
vWF (%)157.9 ± 8.6212.5 ± 16.2<0.01
d-dimer fragments (μg/ml)0.29 ± 0.020.73 ± 0.11<0.01
Fibrinogen (mg/dl)363.0 ± 11.1397.6 ± 19.4NS
  • Data are means ± SE. NS, not significant.