TABLE 2

Summary of suggestive (P ≥ 0.01) single-point (SIBPAL) and multipoint (SEGPATH) linkage results

ChromosomeCytogenetic bandMap position (cM)MarkerSIBPALSEGPATH
1p21.3102.1D1S1588ASF 0.43ASF 0.009
p11.2125.0D1S534ASF 0.003ASF 0.006
q24.2183.5D1S1677ASF 0.32ASF 0.008
2p25.33.8D2S2976ASF 0.009ASF 0.006
p11.196.7D2S1790ASF 0.037ASF 0.005
q11.2102.8GATA176CASF 0.19ASF 0.01
q24.2168.1D2S1776ASF 0.076ASF 0.005
q37.3247.9D2S427ATF 0.006ATF 0.21
4p15.132.2D4S2397ASF 0.099ASF 0.0005
q32.1167.7D4S2417ASF 0.025ASF 0.002
5q35.2185.9D5S1456ASF 0.043ASF 0.003
6p21.3328.8D6S2439ASF 0.087ASF 0.004
p21.142.4D6S1017ASF 0.399ASF 0.003
q16.3106.6D6S1056ASF 0.023ASF 0.004
7q11.2273.2CD36ASF 0.023ASF 0.0025
q31.3134.2D7S1875ASF 0.066ASF 0.001
8q21.1186.4CRHASF 0.003ASF 0.012
9p21.126.8D9S1118ASF 0.098ASF 0.008
q22.192.3D9S1122ASF 0.040ASF 0.0005
q22.296.4D9S257ASF 0.115ASF 0.0008
12q22-q23107.2IGF1ASF 0.005ASF 0.001
q24.33139.6D12S2078ASF 0216ASF 0.0001
q24.33142.1D12S1045ASF 0.019ASF 0.004
AVF 0.007AVF 0.081
ATF 0.015ATF 0.054
13q14.1146.6D13S325ASF 0.174ASF 0.002
q34113.6D13S285ASF 0.313ASF 0.001
14q11.226.2D14S742ASF 0.014ASF 0.007
15q21.154.5D15S659ASF 0.294ASF 0.007
q26.3104.6D15S657ASF 0.082ASF 0.003
16q2165.0D16S3253ASF 0.031ASF 0.003
AVF 0.008AVF 0.04
17q21.142.1D17S2180ASF 0.045ASF 0.0007
q21.354.2D17S1290ASF 0.079ASF 0.004
55.7D17S1301ASF 0.093ASF 0.0007
18q21.150.6D18S851ASF 0.643ASF 0.009
q22.377.8GATA82B02AVF 0.003AVF 0.148
19p13.36.7INSRAVF 0.138AVF 0.01
20p11.2224.5D20S104ASF 0.035ASF 0.005
  • Highly suggestive (P < 0.0023; LOD ≥1.75) and suggestive (P < 0.01; LOD ≥1.18) results are shown in bold. The remaining entries are given for comparison of multipoint and single-point linkage results for a given maker.