TABLE 4

Characteristics of subjects without (Gly/Gly) and with (X/Arg) the Gly972Arg polymorphism in IRS-1 undergoing the hyperglycemic clamp

Gly/GlyX/ArgP
n (M/F)36 (16/20)8 (4/4)
Age (years)33 ± 236 ± 50.62
BMI (kg/m2)24.9 ± 0.923.0 ± 0.90.56
Waist-to-hip ratio0.82 ± 0.030.81 ± 0.010.43
Fasting plasma glucose (mmol/l)4.67 ± 0.084.83 ± 0.130.48
Fasting plasma insulin (pmol/l)48 ± 645 ± 140.31
  • Data are means ± SEM.