TABLE 2

Prevalence of the Pro12→Ala polymorphism of PPAR-γ in type 2 diabetic individuals and control subjects

Type 2 diabetic subjectsNormal control subjects
n2,2011,212
Genotype
 Pro/Pro2,0971,114
 Pro/Ala10396
 Ala/Ala12
Ala allele frequency2.39* (1.93–2.84)4.13 (3.33–4.92)
  • Data are n or % (95% CI).

  • *

    * OR for association of the Ala allele with type 2 diabetes is 0.57 (95% CI 0.43–0.75). χ2 = 16.3; P = 0.000054 vs. the normal control group.