TABLE 2

Plasma C-peptide and insulin concentrations during the different phases of the modified hyperglycemic clamp

Gly/GlyX/ArgP
C-peptide (pmol/l)
 First phase1,548 ± 112949 ± 960.001
 Second phase2,722 ± 1622,021 ± 2120.08
 GLP-1, first phase6,089 ± 3874,614 ± 4630.11
 GLP-1, second phase9,487 ± 5497,570 ± 8320.13
 Max11,678 ± 6688,978 ± 1,0330.06
Insulin (pmol/l)
 First phase320 ± 42146 ± 230.001
 Second phase380 ± 53184 ± 340.03
 GLP-1, first phase1,857 ± 1991,066 ± 1650.12
 GLP-1, second phase4,187 ± 4312,409 ± 3590.12
 Max6,573 ± 6333,646 ± 5080.05
  • Data are means ± SE. first phase, mean of 2.5–10 min; second phase, mean of 80–120 min; GLP first phase, mean of 125–130 min; GLP second phase, mean of 160–180 min; maximal insulin secretion (Max), mean of 182.5–190 min.