TABLE 3

Characteristics of subjects without (Gly/Gly) and with (X/Arg) the Gly972Arg polymorphism in IRS-1 undergoing the OGTT

Gly/GlyX/ArgP
n (M/F)181 (79/92)31 (12/19)
Age (years)32 ± 134 ± 20.56
BMI (kg/m2)24.8 ± 0.324.1 ± 0.80.51
Waist-to-hip ratio0.83 ± 0.010.81 ± 0.010.12
Fasting plasma glucose (mmol/l)4.69 ± 0.054.88 ± 0.080.10
Fasting plasma insulin (pmol/l)47 ± 236 ± 30.03
MCR (ml/kg · min)*7.9 ± 0.37.7 ± 0.40.94
ISI (μmol · kg−1 · min−1 ·  pmol/l−1)*0.075 ± 0.0030.084 ± 0.0080.33
  • Data are means ± SE. Higher values indicate greater insulin sensitivity.