TABLE 3

Median absolute deviation from tRNA and median ratios of other precursor pools to tRNA

[15N]Phe[13C]Leu
Median absolute derivation
 Value
  Tissue fluid0.51280.4607
  Plasma1.60621.1625
  ApoB1001.16221.2845
  KIC0.2516
P value
  Tissue fluid vs. plasma<0.0010.006
  Tissue fluid vs. ApoB100<0.001<0.001
  Plasma vs. ApoB1000.6070.281
  KIC vs. tissue fluid0.030
  KIC vs. plasma<0.001
  KIC vs. ApoB100<0.001
Median ratios
 Value
  Tissue fluid0.89470.8480
  Plasma1.41111.3311
  ApoB1000.57530.6113
  KIC1.0696
P value
  Tissue fluid vs. placebo0.00010.0001
  Tissue fluid vs. ApoB1000.00010.0001
  Plasma vs. ApoB1000.00010.0001
  KIC vs. tissue fluid0.0001
  KIC vs. plasma0.0001
  KIC vs. ApoB1000.0001