TABLE 5

The relative transmission of DRB1-DQA1-DQB1-DPB1 haplotypes in a combined data set of 584 Sardinia, U.K., and U.S. families

DRB1DQA1DQB1DPBITNTPercentage TP TDT <0.05ORT95% CIP PW-TDT <0.05
030105010201020222195.71.2 × 10–531.3(4.0–245.8)3.8 × 10–5
0405030302020118194.79.6 × 10–529.4(3.7–231)3.2 × 10–5
0401030302030126389.71.9 × 10–513.3(3.7–48.0)8.2 × 10–5
0401030302040217289.55.7 × 10–413.9(3.0–64.4)1.1 × 10–4
0401030302020119482.61.8 × 10–37.8(2.4–25.0)8.7 × 10–4
040103030204011032580.55.4 × 10–126.2(3.2–11.8)8.1 × 10–8
0405030302030133978.62.1 × 10–46.6(2.7–16.3)2.4 × 10–4
03010501020103011363281.09.1 × 10–155.8(3.2–10.9)4.5 × 10–7
0404030302030113476.53.9 × 10–24.8(1.4–16.3)1.7 × 10–2
0301050102010201532567.91.5 × 10–33.8(1.9–7.4)3.8 × 10–3
03010501020104011226166.78.1 × 10–63.6(2.0–6.4)1.1 × 10–4
0301050102010101612868.55.4 × 10–43.1(1.6–6.1)9.9 × 10–2
040403030206019660.03.0(0.9–10)
040203030204019660.02.5(0.8–7.6)
0404030302040113861.92.2(0.8–6.0)
030105010201040291047.41.5(0.5–4.0)
010105010301141745.21.2(0.5–2.9)
010105010201111444.01.1(0.5–2.9)
1601010205020401101343.51.1(0.4–2.9)
1601010205020301111640.71.0(0.4–2.5)
010105010401304938.03.2 × 10–21.01.0
070102010201040191537.51.0(0.4–2.5)
1601010205020201223637.90.9(0.5–1.9)
0401030301040182325.87.0 × 10–70.5(0.2–1.4)
070102010201020121313.34.5 × 10–30.3(0.1–1.3)
11-1205010301030121412.52.7 × 10–30.2(0.0–1.1)5.1 × 10–2
11-1205010301040154011.15.7 × 10–70.2(0.1–0.7)13 × 10–2
11-1205010301020132710.01.2 × 10–50.2(0.1–0.7)6.4 × 10–3
0101050104022238.02.7 × 10–50.1(0.0–0.6)4.2 × 10–3
11-120501030104021293.33.2 × 10–70.1(0.0–0.4)3.7 × 10–4
15010102060204012643.02.3 × 10–140.1(0.0–0.2)3.1 × 10–6
  • Data are n or %. Only DRB1-DQB1-DQA1-DPB1 haplotypes detected in at least 15 informative meioses were included. The PW-TDT P values as well as the ORT values were calculated with pairwise comparisons using the DRB1*01-DQA1*0501-DQB1*-0501-DPB1*0401 haplotype as reference. T, transmitted; NT, not transmitted.