TABLE 2

Inhibition of retinopathy by aminoguanidine or aspirin

nDuration (months)Aneurysms per eye
Pericyte ghosts (per 1,000 cells)Acellular capillaries (per mm2 retina)Sudanophilia* (median grade)
(count)(square root)
Normal8601.9 ± 1.41.2 ± 0.66.1 ± 3.43.5 ± 1.40
Diabetes
 Control86025.1 ± 20.64.6 ± 2.217.7 ± 12.713.1 ± 7.91.5
 + Aminoguanidine9603.3 ± 1.91.7 ± 0.77.0 ± 2.65.1 ± 1.40
 + Aspirin86011.6 ± 17.12.8 ± 2.110.2 ± 6.25.2 ± 1.21.0
  • Data are n or means ± SD.

  • *

    * n = 6 per group.