TABLE 2

Metabolic serum parameters

Age (months)Female
Male
ControlLI–IGF-I−/−ControlLI–IGF-I−/−
Cholesterol (mmol/l)32.2 ± 0.24.0 ± 0.2*
43.7 ± 0.24.7 ± 0.2*3.6 ± 0.15.3 ± 0.3*
134.1 ± 0.73.9 ± 0.53.9 ± 0.23.5 ± 0.3
Triglycerides (mmol/l)41.1 ± 0.10.6 ± 0.1†1.2 ± 0.21.1 ± 0.2
FFA (mEq/l)32.0 ± 0.11.7 ± 0.11.7 ± 0.21.4 ± 0.05
Corricosterone (ng/ml)194.3 ± 18.5144.6 ± 31.3111.7 ± 10.1169.0 ± 19.8**
13224 ± 30228 ± 16120 ± 22132 ± 19
  • Data are means ± SEM. Asterisks indicate probability level of random difference between groups by Student’s t test, n = 4–7 in each group.

  • *

    * P < 0.01,

  • **

    ** P < 0.05 for LI–IGF-I−/− versus control.