Effect of a monoclonal anti-NGF antibody on insulin secretion by single β-cells
| Treatment | Glucose (mmol/l) | Percentage of plaque-forming cells | Plaque area (μmol/l) |
|---|---|---|---|
| Control | 5.6 | 41 ± 2 | 1,279 ± 113 |
| 15.6 | 51 ± 3* | 2,299 ± 119* | |
| Monoclonal anti-NGF | 5.6 | 49 ± 3 | 1,371 ± 69 |
| 15.6 | 47 ± 3 | 1,415 ± 67* |
Data are mean ± SE unless otherwise indicated.
* Significance level with respect to its own control in 5.6 mmol/l glucose, n = 6 experiments by duplicate for monoclonal anti-NGF.