TABLE 2

Effect of a monoclonal anti-NGF antibody on insulin secretion by single β-cells

TreatmentGlucose (mmol/l)Percentage of plaque-forming cellsPlaque area (μmol/l)
Control5.641 ± 21,279 ± 113
15.651 ± 3*2,299 ± 119*
Monoclonal anti-NGF5.649 ± 31,371 ± 69
15.647 ± 31,415 ± 67*
  • Data are mean ± SE unless otherwise indicated.

  • *

    * Significance level with respect to its own control in 5.6 mmol/l glucose, n = 6 experiments by duplicate for monoclonal anti-NGF.