TABLE 4

Triglyceride content of islet β-cells and non–β-cells after 48 h of culture

AdditionCellular triglyceride content (pg/ng DNA)
β-CellsNon–β-Cells
Control162 ± 30173 ± 50
0.25 mmol/l oleate652 ± 82*258 ± 24
0.25 mmol/l palmitate389 ± 38*259 ± 51
0.125 mmol/l oleate686 ± 135261 ± 106
0.125 mmol/l palmitate
0.25 mmol/l bromopalmitate251 ± 112235 ± 115
  • Data are means ± SE for five β-cell and six (non–β-cell) independent experiments. Statistical significance of differences between FFA condition and control was calculated by analysis of variance, followed by paired t test with the Bonferroni correction:

  • *

    * P < 0.005,

  • P < 0.05. Statistical significance of differences between islet β-cells and islet endocrine non–β-cells for identical conditions was calculated by analysis of variance, followed by unpaired t test with the Bonferroni correction:

  • P < 0.001.