TABLE 3

NHGLY, NHGO, estimated hepatic oxidation (GO), NHLO, and gluconeogenic flux (GNG flux) (mg · kg−1 · min−1 in glucose equivalents) measured using the AV difference method in the full set of 18-h–fasted conscious dogs

NHGLY=NHGO+GO+NHLOGNG flux
Basal period1.72 ± 0.20=1.90 ± 0.13+0.30+0.30 ± 0.110.78 ± 0.10
Hyperinsulinemic period−0.28 ± 0.15*=0.23 ± 0.16*+0.30+0.06 ± 0.030.88 ± 0.13
  • Data are means ± SE; n = 8,

  • *

    * P < 0.05 basal period (−40–0 min) vs. last 30-min period (intraportal 600 μU · kg−1 · min−1 insulin infusion; 0–180 min).