TABLE 1

Plasma growth hormone, cortisol, serum nonesterified fatty acids, blood β-hydroxybutyrate, lactate, and alanine concentrations before and during hyperinsulinemic stepped hypoglycemic clamps before (Day 1) and after (Day 2) approximately 24 h of hypoglycemia (55 mg/dl, 3.0 mmol/l) in nine subjects who underwent PET studies after hypoglycemia

Nominal glucose (mg/dl)
∼9085756555P
Growth hormone (ng/ml)*
 Day 11.3 ± 0.71.5 ± 1.02.1 ± 1.57.7 ± 2.118.2 ± 2.40.001
 Day 21.1 ± 0.43.5 ± 2.45.1 ± 2.42.6 ± 1.38.4 ± 2.8
Cortisol (μg/dl)
 Day 111.5 ± 1.610.3 ± 1.78.9 ± 1.112.5 ± 1.617.1 ± 1.80.087
 Day 213.4 ± 1.89.8 ± 1.712.4 ± 3.19.8 ± 2.017.4 ± 3.6
Nonesterified fatty acids (μmol/l)
 Day 1381 ± 76104 ± 2679 ± 1479 ± 2066 ± 220.592
 Day 2307 ± 8474 ± 854 ± 748 ± 1045 ± 10
β-Hydroxybutyrate (μmol/l)
 Day 1145 ± 3764 ± 24106 ± 3866 ± 2466 ± 170.927
 Day 2111 ± 2286 ± 2264 ± 1884 ± 2868 ± 19
Lactate (μmol/l)
 Day 11045 ± 1291451 ± 1631349 ± 951308 ± 811824 ± 2310.001
 Day 2963 ± 1151024 ± 68839 ± 90753 ± 691063 ± 94
Alanine (μmol/l)
 Day 1469 ± 54407 ± 26420 ± 421377 ± 46403 ± 330.342
 Day 2291 ± 34311 ± 26310 ± 31257 ± 27259 ± 26
  • Data are means ± SE.

  • *

    * To convert growth hormone to pmol/l, multiply by 44.15;

  • to convert cortisol to nmol/l, multiply by 27.59.