TABLE 1

Administration of multi-antioxidants inhibited hyperglycemia-induced elevation in retinal TBARS, NO, and PKC

TBARS (pmol/mg protein)NO (% normal)PKC (pmol Pi · min−1 · mg−1 protein)
Normal159 ± 17100 ± 2216.5 ± 1.9
Diabetes297 ± 23*165 ± 15*22.7 ± 2.9*
Diabetes + multi-antiox179 ± 21114 ± 2917.3 ± 2.4
Galactose296 ± 23*140 ± 7*21.6 ± 2.1*
Galactose + multi-antiox200 ± 12111 ± 1016.3 ± 0.7
  • Values are mean ± SD of 6–9 rats in each group. Multi-antiox, multi-antioxidant supplements;

  • *

    * P < 0.05 vs. normal rats.

  • P < 0.05 vs. respective untreated diabetic rats or untreated galactose-fed rats.