TABLE 1

Demographic data

Before alloxanAfter alloxan
Age (months)20.8 ± 4.2
Sex (M/F)5/2
Weight (kg)25.2 ± 1.924.5 ± 1.8
Glucose (mmol/l)4.4 ± 0.17.4 ± 1.1*
Insulin (pmol/l)86.0 ± 17.355 ± 7.5*
Glucagon (pg/ml)110 ± 16105 ± 4.1
  • Data are means ± SD or n. The age, sex, weight, and fasting plasma glucose, insulin, and glucagon concentrations in pigs included in protocol 2 (n = 7) before and after alloxan administration (

  • *

    * P < 0.05). Five of these pigs were used in protocol 3.