TABLE 2

Renal glucose production and utilization rates in normal subjects and patients with diabetes in the baseline and the last 40 min of a 220-min hyperinsulinemic clamp period of either euglycemia or hypoglycemia

BaselineEuglycemiaBaselineHypoglycemia
Glucose production
 Normal subjects3.39 ± 1.251.37 ± 1.36*2.44 ± 1.285.50 ± 1.20*
 Diabetic patients2.96 ± 1.310.67 ± 1.36*2.05 ± 1.360.65 ± 1.24*
Glucose utilization
 Normal subjects1.24 ± 1.322.76 ± 1.65*3.08 ± 1.521.01 ± 1.46*
 Diabetic patients1.75 ± 1.625.20 ± 1.93*2.71 ± 1.520.25 ± 1.36*
  • Data are means ± SE in μmol/kg · min.

  • *

    * P < 0.05 for differences between euglycemia and hypoglycemia in diabetes patients versus normal subjects.