TABLE 2

Plasma levels of glucose, lipids, and free fatty acids in mice according to diabetes and treatment with insulin or saline

Control mice treated with PBSDiabetic mice treated with PBSDiabetic mice treated with insulin
N243
Glucose (mmol/l)4.0 ± 0.135.9 ± 11.12.5 ± 0.5
Cholesterol (mmol/l)2.64 ± 0.212.10 ± 0.711.95 ± 0.90
HDL cholesterol (mmol/l)2.14 ± 0.091.72 ± 0.741.58 ± 0.96
Triglycerides (mmol/l)0.96 ± 0.062.48 ± 0.840.70 ± 0.10
Free fatty acids (mmol/l)1.4 ± 0.52.4 ± 2.00.8 ± 0.2
  • Data are means ± SE. Mice were made diabetic by intraperitoneal injection of 200 mg streptozotocin. After at least 2 weeks the mice received intraperitoneal injections of PBS or 14 IU insulin per 100 g body wt as well as subcutaneous injections of PBS or 14 IU insulin per 100 g body wt every 6 h for 24 h. Blood was collected intracardial or intraaortal puncture of mice at once after sacrifice with CO2.