Body composition and fat distribution of aging rats
| young | SO | SC− | VF− | CR | |
|---|---|---|---|---|---|
| n | 6 | 6 | 8 | 6 | 8 |
| VF/SC removed (g) | 0 | 0 | 14.9 ± 1.7 | 15.7 ± 1.3 | 0 |
| Body weight (g) | 291 ± 13 | 478 ± 19* | 451 ± 14* | 452 ± 20* | 303 ± 9 |
| Lean body mass (g) | 264 ± 14 | 373 ± 14* | 364 ± 14* | 372 ± 20* | 266 ± 8 |
| Non-VF fat mass (g) | 21 ± 5 | 82 ± 10* | 65 ± 11* | 75 ± 10* | 32 ± 6 |
| Total VF after study (g) | 5.8 ± 0.9 | 23.4 ± 4.3* | 21.3 ± 1.6* | 4.6 ± 0.7† | 6.1 ± 1.0 |
| Epididymal (g) | 2.9 ± 0.3 | 9.2 ± 1.6* | 8.2 ± 0.7* | 0.1 ± 0.1† | 2.6 ± 0.5 |
| Perinephric (g) | 1.4 ± 0.3 | 8.3 ± 0.7* | 8.1 ± 0.6* | 0.4 ± 0.4† | 1.9 ± 0.5 |
| Mesenteric (g) | 1.5 ± 0.3 | 5.9 ± 0.4* | 4.8 ± 0.6* | 4.1 ± 0.4* | 1.4 ± 0.4 |
young (2-month-old), and old (20-month-old) F1 hybrids of F344 and Brown Norway rats were used in these experiments. The old rats underwent VF removal (VF−), SC fat removal (SC−), sham operation (SO), or CR (see research design and methods). The table depicts the amounts of VF or SC removed at the surgery, body weight, lean body mass, non-VF fat mass, total VF, and epididymal, perinephric, and mesenteric fat, which were determined at killing after the experiments.
* P < 0.001 vs. young and CR;
† P < 0.01 vs. young, CR, and SC−. All data are presented as means ± SE.