TABLE 1

Baseline clinical and biochemical characteristics of NGT, IGT, and diabetic (DM) subjects

ParameterNGTIGTDMP
IGT/NGTDM/NGT
n37611354
Age (years)57 ± 860 ± 860 ± 80.0040.019
Sex (M/F)173/20339/7431/23
BMI (kg/m2)26.4 ± 4.228.0 ± 3.928.8 ± 3.90.0010.001
Total cholesterol (mmol/l)5.64 ± 1.065.76 ± 0.985.42 ± 0.860.5860.318
Triglycerides (mmol/l)1.41 ± 0.761.68 ± 0.761.89 ± 0.970.0060.000
HDL cholesterol (mmol/l)1.56 ± 0.401.50 ± 0.471.32 ± 0.300.9190.300
LDL cholesterol (mmol/l)3.44 ± 0.983.48 ± 0.903.23 ± 0.810.4890.000
HbA1c (%)5.4 ± 0.55.5 ± 0.56.1 ± 0.70.0180.000
Plasma glucose (mmol/l)
 0 min5.39 ± 0.545.84 ± 0.537.19 ± 1.050.0000.000
 120 min5.56 ± 1.268.89 ± 0.9213.10 ± 3.030.0000.000
Free fatty acids (mmol/l)
 0 min0.51 ± 0.240.66 ± 0.230.71 ± 0.290.0000.000
 120 min0.09 ± 0.340.09 ± 0.070.12 ± 0.130.9920.615
Proinsulin (pmol/l)
 0 min4.15 ± 4.305.36 ± 3.969.62 ± 12.090.1240.000
 120 min20.07 ± 24.2229.30 ± 18.5634.91 ± 32.890.0000.000
Insulin (pmol/l)
 0 min68.8 ± 71.484.1 ± 49.5102.3 ± 65.70.1020.003
 120 min259.3 ± 335.1579.8 ± 555.4572.5 ± 568.00.0000.000
C-peptide (pmol/l)
 0 min1,165 ± 5361,416 ± 5341,528 ± 6060.0000.000
 120 min3,649 ± 1,9565,028 ± 1,4164,586 ± 1,9770.0000.003
  • Data are means ± SD. 120 min represents values after oral glucose challenge.