Clinical characteristics of subjects with NGT and IGT according to KIR6.2 E23K genotype
| NGT | IGT | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| E/E | E/K | K/K | E/E | E/K | K/K | |||||
| n (M/F) | 26 (10/16) | 32 (4/28) | 7 (1/6) | 34 (14/20) | 50 (26/24) | 10 (5/5) | ||||
| Age (years) | 44.3 ± 1.3 | 46.6 ± 1.1 | 47.6 ± 1.7 | 57.5 ± 1.3 | 57.7 ± 1.0 | 54.0 ± 2.8 | ||||
| BMI (kg/m2) | 26.6 ± 0.9 | 24.9 ± 0.5 | 26.2 ± 1.5 | 28.7 ± 0.7 | 28.2 ± 0.5 | 29.1 ± 1.1 | ||||
| Fasting plasma glucose (mmol/l) | 4.5 ± 0.1 | 4.7 ± 0.1 | 4.4 ± 0.2 | 6.6 ± 0.1 | 6.6 ± 0.1 | 6.6 ± 0.2 | ||||
| Fasting plasma insulin (pmol/l) | 32 (24–42) | 32 (24–40) | 34 (24–64) | 70 (61–113) | 61 (45–94) | 62 (48–108) | ||||
Data are means ± SE or median (interquartile range). E, glutamic acid; K, lysine. Differences in glucose and insulin levels between the genotypes were tested by ANOVA; P > 0.1 for all comparisons with or without correction for age, sex, and BMI.