TABLE 1

Clinical characteristics of subjects with NGT and IGT according to KIR6.2 E23K genotype

NGT
IGT
E/EE/KK/KE/EE/KK/K
n (M/F)26 (10/16)32 (4/28)7 (1/6)34 (14/20)50 (26/24)10 (5/5)
Age (years)44.3 ± 1.346.6 ± 1.147.6 ± 1.757.5 ± 1.357.7 ± 1.054.0 ± 2.8
BMI (kg/m2)26.6 ± 0.924.9 ± 0.526.2 ± 1.528.7 ± 0.728.2 ± 0.529.1 ± 1.1
Fasting plasma glucose (mmol/l)4.5 ± 0.14.7 ± 0.14.4 ± 0.26.6 ± 0.16.6 ± 0.16.6 ± 0.2
Fasting plasma insulin (pmol/l)32 (24–42)32 (24–40)34 (24–64)70 (61–113)61 (45–94)62 (48–108)
  • Data are means ± SE or median (interquartile range). E, glutamic acid; K, lysine. Differences in glucose and insulin levels between the genotypes were tested by ANOVA; P > 0.1 for all comparisons with or without correction for age, sex, and BMI.