TABLE 3

Association results of the −866G/A polymorphism with type 2 diabetes in obese study populations

n%P*Odds ratio (95% CI) univariate analysisPMultivariate analysisP
Type 2 diabetes
 −866G/G650.32
 −866G/A1060.53
 −866A/A300.15
Control group 1
 −866G/G1370.471.001.00
 −866G/A1170.401.91 (1.29–2.84)0.0012.10 (1.29–3.41)0.003
 −866A/A370.130.0041.71 (0.97–3.01)0.0632.12 (1.05–4.26)0.035
Control group 2
 −866G/G490.491.001.00
 −866G/A390.392.05 (1.22–3.45)0.0072.14 (1.24–3.66)0.006
 −866A/A120.120.0191.88 (0.88–4.05)0.1051.88 (0.85–4.13)0.118
  • * χ2 test for overall comparison between diabetes population and control group 1 and control group 2 populations.

  • P values and their odds ratios for genotypes were calculated by logistic regression analysis.

  • P values for multivariate analyses were adjusted for sex, age (age at onset of type 2 diabetes), and BMI.