TABLE 2

Effects of treatment on signaling protein expression

Protein (arbitrary units/10 μg protein)Troglitazone (n = 7)
Metformin (n = 11)
Pre-RxPost-RxPre-RxPost-Rx
IRS-17.4 ± 1.88.5 ± 2.810.0 ± 1.49.6 ± 1.7
p85α5.4 ± 0.77.5 ± 1.27.2 ± 1.86.0 ± 0.9
p110β4.5 ± 1.35.1 ± 1.53.9 ± 0.54.0 ± 0.8
Akt4.2 ± 1.15.9 ± 2.05.4 ± 1.85.1 ± 1.0
  • Data are means ± SE.