TABLE 3

Characteristics of nondiabetic individuals who underwent the OGTT (stratified by FHD)

No FHD
FHD
PP
AllTTGT + GGP*AllTTGT + GGP*
n2001475316011446
Male/female (n) 86/114 81/6633/200.34§105/55 75/3916/300.95§0.10§
NGT/IGT (n)191/9  142/5 49/4 0.24§143/17162/1241/5 0.95§0.02§
Age (years)32 ± 132 ± 132 ± 2NS38 ± 138 ± 138 ± 1NS<0.001<0.001
BMI (kg/m2)25.2 ± 0.424.5 ± 0.427.0 ± 0.9<0.0526.2 ± 0.0526.0 ± 0.626.6 ± 0.8NS0.050.01
Waist-hip ratio0.84 ± 0.010.84 ± 0.010.85 ± 0.01NS0.85 ± 0.010.84 ± 0.010.87 ± 0.01NS0.160.04
Body fat (%)26 ± 124 ± 129 ± 1<0.0528 ± 128 ± 129 ± 1NS0.020.05
Fasting serum glucose (mmol/l)4.78 ± 0.044.76 ± 0.054.83 ± 0.08NS5.03 ± 0.045.05 ± 0.054.97 ± 0.08NS<0.001<0.001
Glucose 120 min (mmol/l, OGTT)5.28 ± 0.095.17 ± 0.115.56 ± 0.14NS5.93 ± 0.125.94 ± 0.185.90 ± 0.24NS<0.001<0.001
Fasting serum insulin (pmol/l)49 ± 346 ± 357 ± 5<0.00149 ± 347 ± 353 ± 5NS0.100.07
Insulin 120 min (pmol/l, OGTT)294 ± 20255 ± 18404 ± 52<0.01287 ± 15291 ± 19279 ± 28NS0.080.02
  • *

    * TT versus GT + GG (Tukey-Kramer);

  • analysis of variance (four groups);

  • no FHD versus FHD (all);

  • §

    § χ2 test. NGT, normal glucose tolerance.