TABLE 4

Characteristics of NGT individuals who underwent the hyperinsulinemic-euglycemic clamp (stratified by FHD)

No FHD
FHD
PP
AllTTGT + GGP*AllTTGT + GGP*
n12610026835924
Male/female (n)69/5754/4615/110.45§29/5422/377/170.95§0.56§
Age (years)30 ± 130 ± 129 ± 1NS35 ± 134 ± 136 ± 1NS<0.001<0.001
BMI (kg/m2)23.9 ± 0.423.5 ± 0.425.4 ± 1.0NS25.6 ± 0.625.1 ± 0.626.8 ± 1.2NS0.010.06
Waist-hip ratio0.83 ± 0.010.82 ± 0.010.84 ± 0.01NS0.84 ± 0.010.83 ± 0.010.87 ± 0.02NS0.210.07
Body fat (%)22 ± 122 ± 125 ± 2NS27 ± 126 ± 128 ± 1NS<0.001<0.001
Insulin sensitivity index μmol · kg−1 · min−1 · [pmol/l]−10.108 ± 0.0050.116 ± 0.0060.082 ± 0.008<0.05 (NS)0.094 ± 0.0060.096 ± 0.0060.089 ± 0.011NS0.07 (NS)0.01 (NS)
  • *

    * TT versus GT + GG (Tukey-Kramer);

  • analysis of variance (four groups);

  • no FHD versus FHD (all);

  • §

    § χ2 test;

  • adjusted for BMI and % body fat.