TABLE 1

Early dietary antigens and inflammation in the pancreas

HC weaning diet
NIH weaning diet
 Early oral antigen   fed to neonatesPGPGNIH
n343642
Islets unaffected44 ± 2919 ± 1722 ± 21
Islets infiltrated*4 ± 66 ± 118 ± 9
Islets infiltrated (%)12 ± 1830 ± 333 ± 30
Mean overall insulitis rating per rat1.9 ± 1.12.7 ± 1.52.8 ± 1.3
  • Data are means ± SD.

  • *

    * Islet infiltration defined as ≥5 mononuclear cells/islet;

  • and

  • , in each row, numbers with the same symbol are significantly different at P ≤ 0.02 by analyses of variance with least significant difference post-hoc comparisons.