TABLE 2

Tryptophan measurements of media from adenovirus-infected islets

NegAd-LacZAd-IDO
RPMI (control)16.3 ± 0.8
Day 813.3 ± 0.514.4 ± 0.86.7 ± 1.0
Day 1415.2 ± 0.810.4 ± 0.30 (−1.4) ± 0.4
  • Data are means ± SD. In this representative experiment, groups of 400 islets were infected with Ad-LacZ or Ad-IDO or used uninfected (Neg) and cultured for 2 weeks. Samples of media were taken at 8 and 14 days for analysis of tryptophan content. Tryptophan is expressed in nanomoles per milliliter.