TABLE 1

Biological characteristics of Wistar and GK fetuses at 21.5 dpc

Body weight (g)Pancreas weight (mg)Plasma glucose (g/l)Plasma insulin (ng/ml)Plasma GH (ng/ml)
Wistar4.7 ± 0.1 (59)24.7 ± 1.0 (14)0.72 ± 0.02 (46)21.8 ± 2.4 (46)99.8 ± 4.6 (40)
GK4.6 ± 0.1 (45)19.5 ± 0.6* (15)1.15 ± 0.04* (45)6.3 ± 0.4* (45)115.7 ± 6.5 (41)
  • Data are means ± SE. Number of determinations is shown in parentheses. Fetuses were obtained from 4–13 different litters.

  • *

    * P < 0.001 and

  • P < 0.05 as compared with Wistar fetuses.