TABLE 2

Muscle nucleotide content (mmol/kg w.w.)

Soleus
RG
WG
BasalAICA-ribosideBasalAICA-ribosideBasalAICA-riboside
ZMP
    LGND0.94 ± 0.05 (6)*ND1.48 ± 0.1 (6)*ND0.86 ± 0.04 (6)*
    HGND0.85 ± 0.04 (6)*ND1.42 ± 0.1 (6)*ND0.90 ± 0.08 (6)*
AMP
    LG0.09 ± 0.01 (6)0.10 ± 0.01 (6)0.13 ± 0.02 (6)0.11 ± 0.02 (6)0.09 ± 0.03 (6)0.09 ± 0.01 (6)
    HG0.12 ± 0.06 (6)0.09 ± 0.02 (6)0.11 ± 0.03 (6)0.12 ± 0.02 (6)0.10 ± 0.02 (6)0.09 ± 0.01 (6)
ADP
    LG0.54 ± 0.01 (6)0.52 ± 0.02 (6)0.61 ± 0.05 (6)0.57 ± 0.04 (6)0.72 ± 0.11 (6)0.56 ± 0.02 (6)
    HG0.57 ± 0.08 (6)0.55 ± 0.03 (6)0.51 ± 0.07 (6)0.56 ± 0.02 (6)0.63 ± 0.06 (6)0.57 ± 0.03 (6)
ATP
    LG3.74 ± 0.33 (6)3.85 ± 0.17 (6)4.43 ± 0.75 (6)5.05 ± 0.57 (6)6.29 ± 0.49 (6)5.54 ± 0.41 (6)
    HG3.61 ± 0.39 (6)3.67 ± 0.26 (6)5.13 ± 0.34 (6)4.95 ± 0.38 (6)6.65 ± 0.64 (6)5.97 ± 0.29 (6)
  • Data are means ± SE, with (numbers of replicates).

  • *

    * Significant difference from zero (P < 0.001);

  • significant differences from WG and soleus (P < 0.001). ND, not detectable.